DEAE SepFast Large Bead Plus belongs to a group of weak anion ion exchange chromatography media with large particle sizes (100 – 350 μm) and high binding capacity. The base matrix shows excellent flow property and stable physical property, particularly suitable for large-scale purification of biological molecules from viscous and/or crude culture broths or for high speed flow-through polishing applications in which impure components are chromatographically adsorbed from the main product stream.